Staphylococcal scalded skin syndrome - I-Staphylococcal Scalded Skin Syndrome
☆ Kwiziphumo zika-2022 ze-Stiftung Warentest ezivela eJamani, ukwaneliseka kwabathengi ngeModelDerm bekungaphantsi kancinci kunokubonisana nge-telemedicine ehlawulweyo.
Usana olune I-Staphylococcal Scalded Skin Syndrome (Staphylococcal scalded skin syndrome)
References
Staphylococcal Scalded Skin Syndrome yimeko apho ulusu luphalala ngenxa yetyhefu eveliswa ziintlobo ezithile ze-Staphylococcus bacteria. Ayiqhelekanga kubantwana abangaphezu kweminyaka emithandathu. Inokuthi yenzeke nakubantu abadala abanamajoni omzimba abuthathaka okanye iingxaki ezinzulu zezintso. Olona phawu luphambili kukuxobuka kakhulu ulusu kulandela ukudumba. Ubunzima buvela kwii-blister ezimbalwa ukuya kwilahleko ebanzi yolusu, enokubangela ukuhla okukhulu kubushushu bomzimba kunye nokungazinzi kwixinzelelo lwegazi.
Staphylococcal Scalded Skin Syndrome is a disease characterized by denudation of the skin caused by exotoxin producing strains of the Staphylococcus species, typically from a distant site. It usually presents 48 hours after birth and is rare in children older than six years. It may also present in immunocompromised adults or those with severe renal disease. The disorder is characterized by significant exfoliation of skin following cellulitis. The severity may vary from a few blisters to system exfoliation leading to marked hypothermia and hemodynamic instability.
Staphylococcal Scalded Skin Syndrome is a disease characterized by denudation of the skin caused by exotoxin producing strains of the Staphylococcus species, typically from a distant site. It usually presents 48 hours after birth and is rare in children older than six years. It may also present in immunocompromised adults or those with severe renal disease. The disorder is characterized by significant exfoliation of skin following cellulitis. The severity may vary from a few blisters to system exfoliation leading to marked hypothermia and hemodynamic instability.
Staphylococcal scalded skin syndrome (SSSS) and bullous impetigo are infections caused by Staphylococcus aureus. Bullous impetigo is due to the local release of these toxins and thus, often presents with localized skin findings, whereas SSSS is from the systemic spread of these toxins, resulting in a more generalized rash and severe presentation. Both conditions are treated with antibiotics that target S. aureus. These conditions can sometimes be confused with other conditions that result in superficial blistering.
Kwangena inkwenkwe ene 10months ivuza impumlo ingatyi kakuhle. Oogqirha bathi lusulelo oluphezulu lokuphefumla. Kwiintsuku ezimbini kamva, wabuya ngenxa yokuba wayengekho ngcono kwaye wayeneengxaki ezintsha ezifana nokudumba kobuso kunye nolusu oludumbileyo emlonyeni. Kwiintsuku ezimbini ezilandelayo, le nkwenkwe yaba mbi ngakumbi. Iingalo nemilenze yakhe yadumba kwaye ulusu lwakhe lwaqalisa ukuhluma. Emva esibhedlele, oogqirha babona irhashalala ebomvu ebusweni bakhe nakwimiphetho yolusu lwakhe, eyaba mhlophe xa iphathwa. Baye bamxilonga ukuba une staphylococcal scalded skin syndrome (SSSS) kwaye bamqalise ngonyango lokubulala iintsholongwane ngomthambo.
A 10-month-old male presented with rhinorrhea and decreased oral intake and was diagnosed with an upper respiratory infection. Two days later, he returned to the clinic due to a lack of improvement and the onset of new symptoms, including facial edema and perioral skin irritation. That evening, he became febrile at 100.4 °F and went to the emergency department at the local children's hospital. No further workup was done and the parents were instructed to continue with the current treatment regimen. Over the next 48 hours, the patient's symptoms worsened with the new onset of bilateral extremity edema and desquamation. The patient was returned to the emergency department. A physical exam was notable for a blanching, desquamating, erythematous rash on the face and creases of the arms, legs, and groin. A positive Nikolsky sign was reported. A clinical diagnosis of staphylococcal scalded skin syndrome (SSSS) was made, and the patient was started on intravenous clindamycin. This case illustrates a severe presentation of SSSS in a pediatric patient, demonstrating the challenges it poses to diagnosis and treatment.
A 10-month-old male presented with rhinorrhea and decreased oral intake and was diagnosed with an upper respiratory infection. Two days later, he returned to the clinic due to a lack of improvement and the onset of new symptoms, including facial edema and perioral skin irritation. That evening, he became febrile at 100.4 °F and went to the emergency department at the local children's hospital. No further workup was done and the parents were instructed to continue with the current treatment regimen. Over the next 48 hours, the patient's symptoms worsened with the new onset of bilateral extremity edema and desquamation. The patient was returned to the emergency department. A physical exam was notable for a blanching, desquamating, erythematous rash on the face and creases of the arms, legs, and groin. A positive Nikolsky sign was reported. A clinical diagnosis of staphylococcal scalded skin syndrome (SSSS) was made, and the patient was started on intravenous clindamycin. This case illustrates a severe presentation of SSSS in a pediatric patient, demonstrating the challenges it poses to diagnosis and treatment.
Intombazana eneminyaka emi-2 ubudala yabonakala inerhashalala emzimbeni wayo wonke elikhule ngaphezu kweeyure ezingama-48, emva kokulunywa zizinambuzane ebusweni bayo kusuku olungaphambili. Ngethuba lokuhlolwa, wayene-rash ebanzi eyenziwe ngamaqhuma amancinci adityanisiweyo, kwaye xa exutywe kancinane, ulusu lwakhe lwalubonisa iimpawu ze-Nikolsky uphawu. Kwakungekho zimpawu zokuqhambuka okuchaphazela inwebu yakhe yamafinyila. Uvavanyo lwegazi lakhe aluzange lubonise zimpawu zosulelo.
A 2-year-old girl presented a generalised rash with 48 h of evolution, in the context of insect bites on the face on the day before. At observation, she had a generalised micropapular rash with confluent areas and Nikolsky sign. There was no mucosal area affected. Blood cultures were negative.
A 2-year-old girl presented a generalised rash with 48 h of evolution, in the context of insect bites on the face on the day before. At observation, she had a generalised micropapular rash with confluent areas and Nikolsky sign. There was no mucosal area affected. Blood cultures were negative.
I-syndrome ibangelwa yi-epidermolytic exotoxins (exfoliatin) A kunye ne-B, ekhutshwa ngu-S. aureus. Ukuxilongwa kwe- i-staphylococcal scalded skin syndrome (staphylococcal scalded skin syndrome) kubantwana kuhle kakhulu, kunye nesisombululo esipheleleyo phakathi kweentsuku ezili-10 zonyango, kwaye ngaphandle kokuphazamiseka okukhulu. Nangona kunjalo, i- i-staphylococcal scalded skin syndrome (staphylococcal scalded skin syndrome) kufuneka yahlulwe ngononophelo kwi-epidermal necrolysis enetyhefu, ethwala i-prognosis embi.
○ Uxilongo kunye noNyango
I-Misdiagnosis njengezilonda ze-eczema ezifana ne-atopic dermatitis, kunye nokusetyenziswa kwe-ointment ye-steroid kwandisa izilonda. Nceda ufune unyango ngokukhawuleza xa usebenzisa i-antibiotic ointment.
#Bacitracin
#First-generation cephalosporins (e.g. Cefradine)
#Bacterial culture
#Third-generation cephalosporins (e.g. Cefditoren Pivoxil)